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金雀花碱

英文名: cytisine

CAS: 485-35-8      分子式: C11H14N2O

分子量: 190.24200

别名:


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描述

Cytisine, also known as baptitoxine and sophorine, is an alkaloid that occurs naturally in several plant genera, such as Laburnum and Cytisus of the family Fabaceae. It has been used medically to help with smoking cessation. Its molecular structure has some similarity to that of nicotine and it has similar pharmacological effects. Like varenicline, cytisine is a partial agonist of nicotinic acetylcholine receptors (nAChRs). Cytisine has a short half-life of 4.8 hours, and is rapidly eliminated from the body. The use of cytisine for smoking cessation remains relatively unknown outside Eastern Europe.

基本信息
英文名:
cytisine
CAS号.:
485-35-8
别名:
(-)-Cytisine; CYTISINE; Tabex; Tsitafat;Lupinidine; Cytiton; (1R,5S)-3,4,5,6-Tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one; 8H-Pyrido-[1,2-a][1,5]diazocin-8-one, 1,2,3,4,5,6-hexahydro-1,5-methano-; Baptitoxin; Sophorine; Cytitone; Baptitoxine; Laburnin;
分子式:
C11H14N2O
分子量:
190.24200
PSA:
34.03000
LogP:
0.88380
物化属性
外观:
Off-white to tawny crystalline solids
密度:
1.24 g/cm3
熔点:
154-156ºC
沸点:
218ºC (2 mmHg)
闪点:
203.6ºC
储存条件:
Store at RT
安全信息
海关编码:
2933990090
WGK Germany:
3
危险类别码:
R25; R36/37/38
安全说明:
S26-S28-S36/37-S45
危险品标志:
T
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