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杀螺胺

英文名: niclosamide

CAS: 50-65-7      分子式: C13H8Cl2N2O4

分子量: 327.12000

别名: 贝螺杀; 见螺杀; 4'-硝基-2',5-二氯水杨酰苯胺; 5,2'-二氯-4'-硝基水杨酰替苯胺; 血防-67; 百螺杀; 灭绦录; 氯螺消; 氯硝柳胺; 2',5-二氯-4'-硝基水杨酸酰替苯胺;


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描述

Niclosamide (trade name Niclocide) is a teniacide in the anthelmintic family especially effective against cestodes that infect humans and many other animals. It is a salicylanilide compound (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydrobenzamide) also used as a piscicide. While antihelmintics are a drug family used to treat worm infections, niclosamide is used specifically to treat tapeworms and is not effective against other worms such as pinworms or roundworms. It is a chewable tablet taken orally, dosage depending on type of worm and patient's age and/or weight. It is not usually considered the drug of choice for treating cestode infection in humans or animals because of its side effects, though it remains highly effective and is generally inexpensive. Along with oxyclozanide, another tapeworm drug, it has been recently found to display "strong in vivo and in vitro activity against methicillin-resistant Staphylococcus aureus (MRSA)". It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.

基本信息
英文名:
niclosamide
CAS号.:
50-65-7
别名:
hl2447; 2',5-Dichloro-4'-nitrosalicylanilide; 2’,5-dichloro-4’-nitrosalicylanilide; iomezan; Niclosamide; clonitralid; nasemo; iomesan; sulqui; b2353; bay2353; lintex; mato; fenasal; 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide;
分子式:
C13H8Cl2N2O4
分子量:
327.12000
PSA:
95.15000
LogP:
4.45570
物化属性
外观:
white to yellowish odourless crystalline powder
密度:
1.616g/cm3
熔点:
225-230ºC
沸点:
424.5ºC at 760 mmHg
闪点:
210.5ºC
储存条件:
安全信息
信号词:
Warning
海关编码:
2924299090
WGK Germany:
2
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