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英文名: Chlorpheniramine maleate

CAS: 113-92-8      分子式: C20H23ClN2O4

分子量: 390.86100

别名:


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描述

Chlorphenamine (INN), also called chlorpheniramine (USAN and former BAN), commonly marketed in the form of chlorphenamine maleate, is a first-generation alkylamine antihistamine used in the prevention of the symptoms of allergic conditions such as rhinitis and urticaria. Its sedative effects are relatively weak compared to other first-generation antihistamines. Chlorphenamine is one of the most commonly used antihistamines in small-animal veterinary practice. Although not generally approved as an antidepressant or anti-anxiety medication, chlorphenamine appears to have these properties as well. Chlorphenamine is part of a series of antihistamines including pheniramine (Naphcon) and its halogenated derivatives and others including fluorpheniramine, dexchlorpheniramine (Polaramine), brompheniramine (Dimetapp), dexbrompheniramine (Drixoral), deschlorpheniramine, triprolidine (Actifed), and iodopheniramine. The halogenated alkylamine antihistamines all exhibit optical isomerism, and chlorphenamine in the indicated products is racemic chlorphenamine maleate, whereas dexchlorpheniramine is the dextrorotary stereoisomer.

基本信息
英文名:
Chlorpheniramine maleate
CAS号.:
113-92-8
别名:
CHLORPHENAMINE MALEATE; d-chlorpheniramine maleate; teldrin; CHLORPHENAMINE MALEATES; Chloropheniramine Maleate; BISACODYL; (+/-)-CHLORPHENIRAMINE MALEATE SALT; (+/-)-CHLORPHENIRAMINE-D6 MALEATE; CHLORPHENIRAMINE HYDROGEN MALEATE; ibioton; 2-Pyridinepropanamine; CHLOROPHENIRAMINE MALEATE; c-meton; CHLOROPHENAMINEMALEATE; CHLORPHENIRAMINE-D4 MALEATE; ChlorpheniramineMaleate; CHLORTRIMETON; chloropheniramine maleate; alunex; Puermin; Chlorpheniramine (maleate); Haynon; Chlorphenamine maleate; 2-Pyridinepropanamine, γ-(4-chlorophenyl)-N,N-dimethyl-, (Z)-2-butenedioate (1:1); CHLORPHENAMINE HYDROGEN MALEATE, WHO STANDARD; CHLORPHENIRAMINE MALEATE REFERENCE STANDARD; dexchlorpheniramine maleate; Chlorpheniramine Maleate; lorphen; Chlorpheniramine Maleate Salt; piriex; allergin; piriton; P-CHLORO(2-DIMETHYLAMINOETHYL)BENZYLPYRIDINE MALEATE;
分子式:
C20H23ClN2O4
分子量:
390.86100
PSA:
90.73000
LogP:
3.53040
物化属性
外观:
Odorless white crystalline solid or white powder with a bitter taste
密度:
1.107 g/cm3
熔点:
130-135 °C(lit.)
沸点:
379ºC at 760 mmHg
闪点:
183ºC
储存条件:
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
安全信息
海关编码:
2933399090
WGK Germany:
3
危险类别码:
R25
安全说明:
36/37/39-45
危险品标志:
T
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