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齐拉西酮

英文名: ziprasidone

CAS: 146939-27-7      分子式: C21H13ClD8N4OS

分子量: 420.98500

别名:


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描述

Ziprasidone (marketed as Geodon, Zeldox by Pfizer and Zipwell by Actavis) was the fifth atypical antipsychotic to gain approval (February 2001) in the United States. It is approved by the U.S. Food and Drug Administration (FDA) for the treatment of schizophrenia, and acute mania and mixed states associated with bipolar disorder. Its intramuscular injection form is approved for acute agitation in schizophrenic patients for whom treatment with just ziprasidone is appropriate. Ziprasidone is also used off-label for depression, bipolar maintenance, and PTSD. The oral form of ziprasidone is the hydrochloride salt, ziprasidone hydrochloride. The intramuscular form, on the other hand, is the mesylate salt, ziprasidone mesylate trihydrate, and is provided as a lyophilized powder.

基本信息
英文名:
ziprasidone
CAS号.:
146939-27-7
别名:
ziprasidona; UNII-6UKA5VEJ6X; Ziprasidone; Ziprasidone [INN:BAN]; ziprazidone; Zeldox; 5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one; ziprasidonum; Geodon;
分子式:
C21H13ClD8N4OS
分子量:
420.98500
PSA:
76.71000
LogP:
3.94990
物化属性
外观:
Khaki Solid
密度:
1.369 g/cm3
熔点:
213-215°C
沸点:
554.8ºC at 760 mmHg
闪点:
289.3ºC
储存条件:
安全信息
海关编码:
29211980
WGK Germany:
2
危险类别码:
R22; R34; R50/53; R20/21/22
安全说明:
S26; S36/37/39; S45
危险品标志:
C; N
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