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英文名: 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid

CAS: 144060-53-7      分子式: C16H16N2O3S

分子量: 316.37500

别名:


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描述

Febuxostat (INN; trade names Adenuric in Europe and New Zealand, Uloric in the US, Goturic in Latin America, Feburic in Japan) is a drug that inhibits xanthine oxidase, thus reducing production of uric acid in the body. It is used in the treatment of chronic gout and hyperuricemia. Febuxostat was discovered by scientists at the Japanese pharmaceutical company Teijin in 1998. Teijin partnered the drug with TAP Pharmaceuticals in the US and Ipsen in Europe. Ipsen obtained marketing approval for febuxostat from the European Medicines Agency in April 2008, Takeda obtained FDA approval in February 2009, and Teijin obtained approval from the Japanese "Pharmaceuticals and Medical Devices Agency" in 2011.

基本信息
英文名:
2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid
CAS号.:
144060-53-7
别名:
TMX 67; Adenuric; Tei-6720; Uloric; Febuxostat,This product is unavailable;
分子式:
C16H16N2O3S
分子量:
316.37500
PSA:
111.45000
LogP:
3.72318
物化属性
外观:
Crystalline solids
密度:
1.31 g/cm3
熔点:
238-239ºC
沸点:
536.6ºC at 760 mmHg
闪点:
278.3ºC
储存条件:
安全信息
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