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盐酸异丙嗪

英文名: promethazine hydrochloride

CAS: 58-33-3      分子式: C17H21ClN2S

分子量: 320.88000

别名:


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描述

Promethazine is a neuroleptic medication and first-generation antihistamine of the phenothiazine family. The drug has strong sedative and weak antipsychotic effects. It also reduces motion sickness and has antiemetic and anticholinergic properties (via its action on the Dopamine receptor D2). In some countries it is prescribed for insomnia when benzodiazepines are contraindicated. It is available in many countries under many brand names. Promethazine was developed in the mid 1940s when a team of scientists from Rhône-Poulenc laboratories were able to synthesize it from phenothiazine and a diamine side chain of diphenhydramine.

基本信息
英文名:
promethazine hydrochloride
CAS号.:
58-33-3
别名:
10H-Phenothiazine-10-ethanamine, N,N,α-trimethyl-, monohydrochloride; Promethazine hydrochloride; Promethazine Hydrochloride;
分子式:
C17H21ClN2S
分子量:
320.88000
PSA:
31.78000
LogP:
5.10640
物化属性
外观:
White or gray-white powder
密度:
1.131 g/cm3
熔点:
230-232°C
沸点:
403.7ºC at 760 mmHg
闪点:
198ºC
储存条件:
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
安全信息
符号:
GHS07、GHS09
信号词:
Warning
危害声明:
H302 + H332; H315; H317; H319; H335; H411
警示性声明:
P261; P273; P280; P305 + P351 + P338
海关编码:
2933699090
WGK Germany:
3
危险类别码:
R22; R36/37/38
安全说明:
S26-S36
危险品标志:
Xn
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