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醋酸氟轻松

英文名: Fluocinolone Acetonide Acetate

CAS: 356-12-7      分子式: C26H32F2O7

分子量: 494.52500

别名:


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描述

Fluocinonide (Fluonex, Lidex, Lidex-E, Lonide, Lyderm, and Vanos) is a potent glucocorticoid used topically as an anti-inflammatory agent for the treatment of skin disorders such as eczema and seborrhoeic dermatitis. It relieves itching, redness, dryness, crusting, scaling, inflammation, and discomfort. The usual prescription concentration is 0.05% as a topical cream, ointment, solution, or gel. The application area should normally not be covered after application. In certain cases, the physician may recommend the use of an occlusive dressing after application to increase the rate and depth of absorption. The frequency of application depends on the condition being treated and the area affected, but most often it should be applied 2 to 4 times a day. Fluocinonide ranks as a "high-potency" (second-highest rank) topical corticosteroid. Minimal amounts should be used for a minimal length of time to avoid the occurrence of adverse effects.[medical citation needed]. Fluocinonide should not be used if infection is present. It should not be applied to the eyes or to sensitive areas such as the genitals or anus.[medical citation needed]; A common potential adverse effect is skin atrophy (thinning of the skin). Systemic absorption of topical corticosteroids can produce reversible hypothalamic-pituitary-adrenal axis (HPA) suppression, manifestations of Cushing's syndrome, hyperglycemia, and glucosuria in some patients. Fluocinonide should be used with caution when treating children, pregnant women, nursing mothers, and anyone using the medication for longer than two weeks. Fluocinonide is used in veterinary medicine. It is a treatment for allergies in dogs. Natural systemic cortisol concentrations can be suppressed for weeks after one week of topical exposure.

基本信息
英文名:
Fluocinolone Acetonide Acetate
CAS号.:
356-12-7
别名:
fluocinonide;
分子式:
C26H32F2O7
分子量:
494.52500
PSA:
99.13000
LogP:
2.93760
物化属性
外观:
White crystalline powder
密度:
1.34g/cm3
熔点:
309ºC
沸点:
591.1ºC at 760mmHg
闪点:
311.3ºC
储存条件:
安全信息
海关编码:
2937210000
危险类别码:
R28
安全说明:
S22; S25; S28; S36/37/39; S45
危险品标志:
T+
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