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阿那曲唑

英文名: anastrozole

CAS: 120511-73-1      分子式: C17H19N5

分子量: 293.36600

别名:


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描述

Anastrozole (INN) (marketed under the trade name Arimidex by AstraZeneca) is a non-steroidal aromatase-inhibiting drug approved for treatment of breast cancer after surgery, as well as for metastasis in both pre and post-menopausal women. The severity of breast cancer can be increased by estrogen, as sex hormones cause hyperplasia, and differentiation at estrogen receptor sites. Anastrozole works by inhibiting the synthesis of estrogen. The patent on Arimidex by AstraZeneca expired June 2010. It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system.

基本信息
英文名:
anastrozole
CAS号.:
120511-73-1
别名:
ANASTRAZOLE; Anastrol; 2,2'-(5-((1H-1,2,4-Triazol-1-yl)methyl)-1,3-phenylene)bis(2-methylpropanenitrile); Anatrozole; ZD-1033;
分子式:
C17H19N5
分子量:
293.36600
PSA:
78.29000
LogP:
2.92876
物化属性
外观:
Crystalline solids
密度:
1.08 g/cm3
熔点:
81-82°C
沸点:
469.7ºC at 760 mmHg
闪点:
储存条件:
Store in original container in a cool dark place.
安全信息
海关编码:
2933990090
危险类别码:
R36/37/38
安全说明:
S26; S37/39
危险品标志:
Xi
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