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左旋多巴

英文名: L-dopa

CAS: 59-92-7      分子式: C9H11NO4

分子量: 197.18800

别名:


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描述

L-DOPA (alt., L-3,4-dihydroxyphenylalanine) is a chemical that is made and used as part of the normal biology of humans, some animals and plants. Some animals and humans make it via biosynthesis from the amino acid L-tyrosine. L-DOPA is the precursor to the neurotransmitters dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline) collectively known as catecholamines. Furthermore, L-DOPA itself mediates neurotrophic factor release by the brain and CNS. L-DOPA can be manufactured and in its pure form is sold as a psychoactive drug with the INN levodopa; trade names include Sinemet, Pharmacopa, Atamet, Stalevo, Madopar, and Prolopa. As a drug, it is used in the clinical treatment of Parkinson's disease and dopamine-responsive dystonia. L-DOPA has a counterpart with opposite chirality, D-DOPA. As is true for many molecules, the human body produces only one of these isomers (the L-DOPA form). The enantiomeric purity of L-DOPA may be analyzed by determination of the optical rotation or by chiral thin-layer chromatography (TLC).

基本信息
英文名:
L-dopa
CAS号.:
59-92-7
别名:
l-dop; Dopar; Doprin; Parda; L-3,4-dihydroxyphenylalanine; Doparl; Beldopa; 3,4-dihydroxy-L-phenylalanine; Levopa; Bendopa; L-Tyrosine, 3-hydroxy-; L-DOPA; Ledopa; Levodopa;
分子式:
C9H11NO4
分子量:
197.18800
PSA:
103.78000
LogP:
0.75250
物化属性
外观:
White or White crystalline powder
密度:
熔点:
276-278 °C(lit.)
沸点:
闪点:
储存条件:
2-8°C
安全信息
符号:
GHS07
信号词:
Warning
危害声明:
H302; H315; H319; H335
警示性声明:
P280; P301 + P312 + P330; P304 + P340 + P312; P305 + P351 + P338; P337 + P313
海关编码:
2932999099
WGK Germany:
3
危险类别码:
R22; R36/37/38; R20/21/22
安全说明:
S26; S36; S24/25
危险品标志:
Xn
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