炎黄化工网-化工平台-中国化工网-灰黄霉素-126-07-8-C17H17ClO6

英文名: griseofulvin

CAS: 126-07-8 分子式: C17H17ClO6

分子量: 352.76600

别名:

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描述

Griseofulvin (trade names: Gris-peg and Grifulvin V) is an orally administered antifungal drug. It is used both in animals and humans, to treat fungal infections of the skin (commonly known as ringworm) and nail fungus. It was discovered in the culture broth of certain species of the mold Penicillium in 1939. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. It is produced industrially by fermenting the fungus Penicillium patulum.

基本信息

英文名:

griseofulvin

CAS号.:

126-07-8

别名:

Griseofulvin Permeability Diameter; (1’S,6’R)-7-chloro-2’,4,6-trimethoxy-6’-methylspiro[benzofuran-2(3H),1’-[2]cyclohexene]-3,4’-dione; Spiro[benzofuran-2(3H),1‘-[2]cyclohexene]-3,4‘-dione, 7-chloro-2‘,4,6-trimethoxy-6‘-methyl-, (1‘S-trans)-; (1’S-trans)- 7-chloro-2’,4,6-trimethoxy-6’-methylspiro[benzofuran-2(3H),1’-cyclohex-2’-ene]-3,4’-dione; (2S,5'R)-7-chloro-3',4,6-trimethoxy-5'-methylspiro[1-benzofuran-2,4'-cyclohex-2-ene]-1',3-dione; Griseofulvin; (+)-Griseofulvin; 7-chloro-4,6-dimethoxycoumaran-3-one-2-spiro-1’-(2’-methoxy-6’-methylcyclohex-2’-en-4’-one);

分子式:

C17H17ClO6

分子量:

352.76600

PSA:

71.06000

LogP:

2.81030

物化属性

外观:

White to pale creamy crystalline powder odorless or near odorless.

密度: