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泼尼松龙

英文名: prednisolone

CAS: 50-24-8      分子式: C21H28O5

分子量: 360.44400

别名:


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描述

Prednisolone is a synthetic glucocorticoid, a derivative of cortisol, used to treat a variety of inflammatory and autoimmune conditions and some cancers. It is the active metabolite of the drug prednisone and is used especially in patients with liver failure, as these individuals are unable to metabolize prednisone into active prednisolone; it is primarily metabolized via the liver enzyme, 11-β-hydroxydehydrogenase. Adverse effects are not generally seen with short term therapy, but weight gain, impaired immune response, and behavioral disturbances commonly occur with longer durations of treatment. It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system.

基本信息
英文名:
prednisolone
CAS号.:
50-24-8
别名:
STEROLONE; ulacort; Pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-, (11β)-; steran; dicortol; eazolind; prednis; deltaf; solone; hydeltra; predonin; Prednisolone;
分子式:
C21H28O5
分子量:
360.44400
PSA:
94.83000
LogP:
1.55760
物化属性
外观:
Crystalline solids
密度:
1.31 g/cm3
熔点:
240 °C (dec.)(lit.)
沸点:
570.6ºC at 760 mmHg
闪点:
313ºC
储存条件:
-20ºC Freezer
安全信息
海关编码:
2937229000
WGK Germany:
3
危险类别码:
R22
安全说明:
S22; S45; S36/37/39; S26; S16
危险品标志:
Xn
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