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来氟洛米

英文名: leflunomide

CAS: 75706-12-6      分子式: C12H9F3N2O2

分子量: 270.20700

别名:


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描述

Leflunomide (original brand name Arava) is an immunosuppressive disease-modifying antirheumatic drug (DMARD), used in active moderate-to-severe rheumatoid arthritis and psoriatic arthritis. It is a pyrimidine synthesis inhibitor that works by inhibiting dihydroorotate dehydrogenase. Bottle of Leflunomide (Arava) and tablet

基本信息
英文名:
leflunomide
CAS号.:
75706-12-6
别名:
Leflunomida; Leflunomidum; 5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide; Leflunomide; lefunamide;
分子式:
C12H9F3N2O2
分子量:
270.20700
PSA:
55.13000
LogP:
3.32710
物化属性
外观:
Gray-White crystalline solid
密度:
1.392 g/cm3
熔点:
163-168°C
沸点:
289.3ºC at 760 mmHg
闪点:
128.8ºC
储存条件:
2-8ºC
安全信息
符号:
GHS06
信号词:
Dangerous
危害声明:
H301; H315; H319; H335
警示性声明:
P261; P301 + P310; P305 + P351 + P338
海关编码:
2934999090
WGK Germany:
3
危险类别码:
R22; R36/37/38
安全说明:
S26; S36
危险品标志:
Xn
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