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佐米曲普坦

英文名: zolmitriptan

CAS: 139264-17-8      分子式: C16H21N3O2

分子量: 287.35700

别名:


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描述

Zolmitriptan is a selective serotonin receptor agonist of the 1B and 1D subtypes. It is a triptan, used in the acute treatment of migraine attacks with or without aura and cluster headaches. Zolmitriptan is marketed by AstraZeneca with the brand names Zomig, Zomigon (Argentina, Canada & Greece), AscoTop (Germany) and Zomigoro (France). In 2008, Zomig generated nearly $154 million in sales. AstraZeneca's U.S. patent on Zomig tablets expired on November 14, 2012, and its pediatric exclusivity extension expired on May 14, 2013. The patent in certain European countries has already expired too, and generic drug maker Actavis released a generic version in those countries, starting in March 2012.

基本信息
英文名:
zolmitriptan
CAS号.:
139264-17-8
别名:
(S)-4-[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl]-2-oxazolidinone; Zolmitriptan; (4R)-4-[[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]methyl]oxazolidin-2-one;
分子式:
C16H21N3O2
分子量:
287.35700
PSA:
57.36000
LogP:
2.25170
物化属性
外观:
密度:
1.217 g/cm3
熔点:
136-141ºC
沸点:
563.3ºC at 760 mmHg
闪点:
294.5ºC
储存条件:
Store in original container in a cool dark place.
安全信息
海关编码:
2934999090
危险类别码:
R36/37/38
安全说明:
S26-S36
危险品标志:
Xi
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